产品货号：
Z17766
中文名称：
Ghrelin/GHRL抗体
英文名称：
Anti-Ghrelin/GHRL Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Ghrelin/GHRL Antibody |
| 指标别名 | Appetite regulating hormone;Ghrelin Obestatin;GHRL;Motilin related peptide;MTLRP;obestatin;Protein M46 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | IHC |
| 基因名称 | GHRL |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence of human Ghrelin/GHRL (QRKESKKPPAKLQPR). |
| 成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | This gene encodes the ghrelin-obestatin preproprotein that is cleaved to yield two peptides,ghrelin and obestatin.Ghrelin is a powerful appetite stimulant and plays an important role in energy homeostasis.Its secretion is initiated when the stomach is empty,whereupon it binds to the growth hormone secretagogue receptor in the hypothalamus which results in the secretion of growth hormone (somatotropin).Ghrelin is thought to regulate multiple activities,including hunger,reward perception via the mesolimbic pathway,gastric acid secretion,gastrointestinal motility,and pancreatic glucose-stimulated insulin secretion.It was initially proposed that obestatin plays an opposing role to ghrelin by promoting satiety and thus decreasing food intake,but this action is still debated.Recent reports suggest multiple metabolic roles for obestatin,including regulating adipocyte function and glucose metabolism.Alternative splicing results in multiple transcript variants.In addition,antisense transcripts for this gene have been identified and may potentially regulate ghrelin-obestatin preproprotein expression.\ |
| Uniprot ID | Q9UBU3 |
| 推荐配套试剂 | Biorab recommends HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P). |
| 基因名全称 | ghrelin and obestatin prepropeptide |
| 蛋白名全称 | Appetite-regulating hormone |
| 推荐稀释比 | Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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